Description

Boc-L-Ser(Chx)-Oh is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of L-serine with a cyclohexyl (Chx) ester protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of serine residues into peptide chains.
• Pharmaceutical Research: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a precursor for creating peptide conjugates for drug delivery systems or diagnostic agents.
• Chemical Biology: Employed in the synthesis of peptide fragments for studying protein-protein interactions and enzyme function.
• Protecting Group Chemistry: Demonstrates the application of Boc and cyclohexyl ester protecting groups in multi-step organic synthesis.

Basic Information

Product Name	Boc-L-Ser(Chx)-Oh
CAS No.	221057-18-7
Molecular Formula	C14H25NO5
Molecular Weight	287.35 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid cyclohexyl ester; N-(tert-Butoxycarbonyl)-L-serine cyclohexyl ester; Boc-Ser(Chx)-OH; Boc-L-serine cyclohexyl ester; Cyclohexyl N-[(1,1-dimethylethoxy)carbonyl]-L-serinate; L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, cyclohexyl ester
EINECS	Contact for details

Quality Control

Our Boc-L-Ser(Chx)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-10.0° to -15.0° (c=1 in MeOH)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.