Description

3-Fluoro-4-(Methylthio)Phenylboronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce fluorinated aryl motifs with a methylthio substituent, key for modulating biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine and sulfur-containing moiety enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific thermal, optical, or chemical resistance properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and material science.
• Ligand & Catalyst Preparation: Used to synthesize sophisticated ligands for transition metal catalysis.

Basic Information

Product Name	3-Fluoro-4-(Methylthio)Phenylboronic Acid
CAS No.	221030-80-4
Molecular Formula	C7H8BFO2S
Molecular Weight	185.99 g/mol
Synonyms	(3-Fluoro-4-(methylthio)phenyl)boronic acid; 3-Fluoro-4-methylsulfanylbenzeneboronic acid; 4-Borono-2-fluoro-1-(methylthio)benzene; B-[3-Fluoro-4-(methylthio)phenyl]boronic acid; 3-Fluoro-4-(methylmercapto)benzeneboronic acid; 3-Fluoro-4-(methylsulfanyl)phenylboronic acid; 221030-80-4
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylthio)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture will compromise purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.