Description

Sorbitol Dehydrogenase is a highly specific oxidoreductase enzyme that catalyzes the reversible conversion of sorbitol to fructose. This biochemical specificity makes it an indispensable tool for enzymatic analysis and diagnostic applications, particularly in clinical chemistry and life science research. It is essential for manufacturers and research institutions requiring precise, reliable enzymatic reagents for metabolic pathway studies and diagnostic kit formulation.

Application

• Clinical Diagnostic Kits: A key component in enzymatic assays for the quantitative determination of sorbitol, fructose, and related metabolites in blood and serum samples, aiding in the diagnosis and monitoring of conditions like diabetes.
• Biochemical Research: Used as a critical reagent in metabolic studies, particularly for investigating the polyol pathway and its role in diabetic complications and cellular osmotic regulation.
• Food & Beverage Analysis: Employed in enzymatic methods for the accurate quantification of sugar alcohols (like sorbitol) and sugars in food products, ensuring quality control and nutritional labeling compliance.
• Pharmaceutical Development: Utilized in enzymatic synthesis and as an analytical tool in drug development processes targeting metabolic disorders.
• Enzyme Manufacturing & Supply: Supplied to diagnostic and biotechnology companies as a high-purity raw material for their proprietary reagent and kit production.

Basic Information

Product Name	Sorbitol Dehydrogenase
CAS No.	220983-94-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SDH; L-Iditol Dehydrogenase; Polyol Dehydrogenase; Sorbitol Dehydrogenase (NAD+); Sorbitol Dehydrogenase (NAD(P)+); Sorbitol:NAD+ 5-oxidoreductase; EC 1.1.1.14; Ketose reductase
EINECS	Contact for details

Quality Control

Our Sorbitol Dehydrogenase is produced and tested under stringent quality management systems. Each batch is characterized for specific activity, purity, and stability to ensure reliable performance in sensitive diagnostic and research applications. A comprehensive Certificate of Analysis (COA), detailing activity units, protein content, and impurity profiles, is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Protein Content (Biuret)	Contact for details
Purity (SDS-PAGE)	≥ 90%
pH (in solution)	6.0 - 8.0
Stabilizers / Additives	May contain buffer salts (e.g., phosphate, Tris)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.