Description

3-Pyrrolidineacetonitrile, 4-Methylene-1-(Trifluoroacetyl)- (9Ci) is a high-value, specialized organic intermediate featuring a reactive pyrrolidine scaffold and a trifluoroacetyl protecting group. This compound is critical for synthetic chemists as it enables the efficient construction of complex nitrogen-containing heterocycles, which are core structures in many modern pharmaceuticals. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of pyrrolidine-based drug candidates, including protease inhibitors, kinase inhibitors, and neurological agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Chemical Research & Development: Serves as a versatile precursor for exploring new chemical space in medicinal chemistry and material science.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Ligand and Catalyst Development: Useful for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Pyrrolidineacetonitrile, 4-Methylene-1-(Trifluoroacetyl)- (9Ci)
CAS No.	220951-48-4
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	4-Methylene-1-(trifluoroacetyl)-3-pyrrolidineacetonitrile; 1-(Trifluoroacetyl)-4-methylenepyrrolidine-3-acetonitrile; 4-Methylene-1-(trifluoroacetyl)pyrrolidine-3-acetonitrile; 3-Pyrrolidineacetonitrile, 4-methylene-1-(trifluoroacetyl)-; 220951-48-4; 4-Methylenepyrrolidine-3-acetonitrile, 1-(trifluoroacetyl)-
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidineacetonitrile, 4-Methylene-1-(Trifluoroacetyl)- (9Ci) is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.