Description

4',7-Dihydroxyisoflavone-D3 is a deuterium-labeled analog of the natural isoflavone, 4',7-Dihydroxyisoflavone, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity, isotopically labeled compound is critical for ensuring accuracy and reliability in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and analytical chemistry industries who require precise measurement of isoflavones and their metabolites.

Application

• Internal Standard for LC-MS/MS: Primary use as a stable, isotopically labeled internal standard for the accurate quantification of 4',7-Dihydroxyisoflavone and related compounds in complex biological matrices.
• Pharmacokinetic Research: Enables precise tracking of drug metabolism, absorption, distribution, and excretion (ADME) studies for isoflavone-based pharmaceuticals.
• Biomarker Analysis: Used in clinical and nutritional research to measure isoflavone levels in plasma, serum, and urine for biomarker discovery and validation.
• Method Development & Validation: Critical for developing and validating robust, GLP-compliant analytical methods in contract research organizations (CROs) and regulatory labs.
• Nutraceutical & Food Testing: Supports quality assurance and authenticity testing in the dietary supplement and functional food industries for soy and red clover extracts.
• Reference Material: Serves as a certified reference material (CRM) for instrument calibration and ensuring analytical method precision.

Basic Information

Item	Detail
Product Name	4',7-Dihydroxyisoflavone-D3
CAS No.	220930-96-1
Molecular Formula	C15H7D3O4
Molecular Weight	257.26 g/mol
Synonyms	7-Hydroxydaidzein-D3; Daidzein-2,3,4-D3; 4',7-Dihydroxyisoflavone-2,3,4-D3; 7,4'-Dihydroxyisoflavone-D3; Isoflavone, 4',7-dihydroxy-2,3,4-D3; Deuterated Daidzein; [2,3,4-2H3]-4',7-Dihydroxyisoflavone; 7,4'-Dihydroxy-2,3,4-trideuterioisoflavone
EINECS	Contact for details

Quality Control

Every batch of 4',7-Dihydroxyisoflavone-D3 is manufactured and tested under strict quality systems. We guarantee high chemical and isotopic purity as verified by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, isotopic enrichment, and solvent content. Our quality commitment ensures the material is suitable for the most demanding GLP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. For long-term storage, keep desiccated at -20°C. Allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to yellow powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Isotopic Enrichment	≥ 99.0% (by MS)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.