Description

1-(5-Deoxy-5-Fluoro-α-D-Arabinofuranosyl)-2-Nitroimidazole Reference Standard For [18F]Faza is a high-purity chemical standard, specifically designed for the calibration and validation of analytical methods in radiopharmaceutical development. This compound is critically important as a non-radioactive precursor and reference material for the synthesis of [18F]FAZA, a positron emission tomography (PET) imaging agent. It is essential for researchers and manufacturers in the nuclear medicine and radiopharmaceutical sectors who require reliable, traceable reference standards to ensure the quality, safety, and efficacy of diagnostic imaging agents.

Application

• Primary Reference Standard for the synthesis and quality control of the PET tracer [18F]FAZA.
• Calibration and validation of analytical instruments, including High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) systems.
• Method development and verification in radiopharmaceutical research laboratories.
• Use as a non-radioactive training compound for synthesis optimization of [18F]FAZA.
• Critical component in stability studies and impurity profiling for regulatory submissions (e.g., to FDA, EMA).
• Quality assurance in Good Manufacturing Practice (GMP) production environments for diagnostic radiopharmaceuticals.

Basic Information

Product Name	1-(5-Deoxy-5-Fluoro-α-D-Arabinofuranosyl)-2-Nitroimidazole Reference Standard For [18F]Faza
CAS No.	220793-03-3
Molecular Formula	C11H13FN3O6
Molecular Weight	302.24 g/mol
Synonyms	FAZA Precursor; 1-(5-Deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitro-1H-imidazole; 2-Nitroimidazole Riboside Derivative; [18F]FAZA Reference Standard; 5'-Deoxy-5'-fluoro-arabinofuranosyl-2-nitroimidazole; Nitroimidazole Nucleoside; Hypoxia Imaging Agent Precursor; FAZA Cold Standard
EINECS	Contact for details

Quality Control

This reference standard is produced under stringent quality control protocols to ensure exceptional purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality system is designed to support compliance with pharmaceutical and radiopharmaceutical industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.