Description

Ethyl 2-Fluoro-4-(trifluoromethyl)phenylacetate is a high-value fluorinated aromatic ester building block. This compound is critical for introducing the 2-fluoro-4-(trifluoromethyl)phenyl moiety into advanced molecular architectures, significantly influencing their physicochemical and biological properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed to incorporate fluorinated aromatic units into specialty polymers, improving their thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new reactions and creating compound libraries for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	Ethyl 2-Fluoro-4-(Trifluoromethyl)Phenylacetate
CAS No.	220530-99-4
Molecular Formula	C11H10F4O2
Molecular Weight	250.19 g/mol
Synonyms	Ethyl (2-Fluoro-4-(trifluoromethyl)phenyl)acetate; 2-Fluoro-α-(trifluoromethyl)benzeneacetic Acid Ethyl Ester; Acetic Acid, [2-Fluoro-4-(trifluoromethyl)phenyl]-, Ethyl Ester; Ethyl 2-Fluoro-4-(trifluoromethyl)benzeneacetate; Ethyl (2-Fluoro-4-trifluoromethylphenyl)acetate; [2-Fluoro-4-(trifluoromethyl)phenyl]acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Fluoro-4-(trifluoromethyl)phenylacetate is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.