Description

2-(Trifluoromethoxy)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a phenylacetic acid core and a trifluoromethoxy substituent, makes it a versatile intermediate for creating molecules with enhanced metabolic stability and lipophilicity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optic materials.
• Chemical Research & Development: A valuable building block for medicinal chemistry, exploring structure-activity relationships (SAR) and creating compound libraries.
• Advanced Polymer Modification: Used to introduce fluorinated aromatic units into polymer backbones to alter thermal and chemical resistance properties.

Basic Information

Product Name	2-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	220239-67-8
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-(Trifluoromethoxy)benzeneacetic acid; α-(Trifluoromethoxy)phenylacetic acid; (2-Trifluoromethoxyphenyl)acetic acid; 2-(Trifluoromethoxy)benzylcarboxylic acid; o-(Trifluoromethoxy)phenylacetic acid; 2-(Trifluoromethoxy)benzenecarboxylic acid, α-form; 220239-67-8; 2-(Trifluoromethoxy)phenylacetic acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.