Description

Boc-L-Tyr-Ol is a protected derivative of the amino acid L-Tyrosine, featuring a tert-butoxycarbonyl (Boc) protecting group on the amine and a reduced alcohol (ol) functionality on the carboxylate. This compound is a crucial building block in solid-phase peptide synthesis (SPPS) and organic chemistry, where it serves as a key intermediate for the controlled introduction of tyrosine residues. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing peptide-based therapeutics, diagnostic agents, and novel bioactive compounds.

Application

• Peptide Synthesis Intermediate: A fundamental building block for the incorporation of tyrosine into custom peptide sequences during SPPS and solution-phase synthesis.
• Pharmaceutical Research: Used in the research and development of peptide hormones, enzyme inhibitors, and other therapeutic peptides.
• Bioconjugation: Serves as a starting material for creating tyrosine-containing linkers or tags used in antibody-drug conjugates (ADCs) and protein labeling.
• Chemical Biology Probes: Employed in the synthesis of probes and tools for studying protein-protein interactions and enzyme activity.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of more complex organic molecules and natural product analogs.

Basic Information

Product Name	Boc-L-Tyr-Ol
CAS No.	220237-31-0
Molecular Formula	C₁₄H₂₁NO₄
Molecular Weight	267.32 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propan-1-ol; N-(tert-Butoxycarbonyl)-L-tyrosinol; Boc-Tyr-ol; Boc-L-Tyrosine-ol; N-Boc-L-tyrosinol; tert-Butyl (1S)-1-(hydroxymethyl)-2-(4-hydroxyphenyl)ethylcarbamate; L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, (1-hydroxymethyl-2-(4-hydroxyphenyl)ethyl) ester
EINECS	Contact for details

Quality Control

Our Boc-L-Tyr-Ol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.