Description

2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electron-transport materials.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains into polymers, improving their chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	220227-66-7
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	2-Fluoro-α-(trifluoromethyl)phenylacetic Acid; [2-Fluoro-5-(trifluoromethyl)phenyl]acetic Acid; 5-(Trifluoromethyl)-2-fluorophenylacetic Acid; 2-Fluoro-5-trifluoromethylphenylacetic Acid; α-(2-Fluoro-5-(trifluoromethyl)phenyl)acetic Acid; 220227-66-7; F-TFM-PAA
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.