Description

(R)-(+)-2,2'-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]-1,1'-Binaphthyl is a highly specialized, chiral bisphosphine ligand crucial for enabling asymmetric synthesis in advanced chemical manufacturing. Its core value lies in providing exceptional enantioselectivity and catalytic activity in transition metal-catalyzed reactions, which is essential for producing single-enantiomer intermediates. This product is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing and scaling up high-value chiral compounds.

Application

• Asymmetric hydrogenation of prochiral olefins, ketones, and imines for pharmaceutical intermediate synthesis.
• Enantioselective C-C bond-forming reactions, including cross-coupling and allylic substitution.
• Catalyst ligand in the synthesis of chiral active pharmaceutical ingredients (APIs) and agrochemicals.
• Key component in homogeneous catalysis research for developing new synthetic methodologies.
• Production of specialty flavors, fragrances, and electronic chemicals requiring high optical purity.

Basic Information

Product Name	(R)-(+)-2,2'-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]-1,1'-Binaphthyl
CAS No.	220196-32-7
Molecular Formula	C60H28F24P2
Molecular Weight	1195.78 g/mol
Synonyms	(R)-(+)-DTBM-SEGPHOS; (R)-DTBM-SEGPHOS; (R)-5,5'-Bis[bis(3,5-bis(trifluoromethyl)phenyl)phosphino]-4,4'-bi-1,3-benzodioxole; (R)-DTBM-Segphos; (R)-3,3'-Bis[bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-2,2'-bis(1,3-benzodioxolyl); SEGPHOS, 3,3'-bis[bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-, (R)-; (R)-DTBM-SegPhos ligand
EINECS	Contact for details

Quality Control

Our (R)-(+)-DTBM-SEGPHOS is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and key impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.