Description

1,5-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Pentane is a specialized, high-value organophosphorus ligand featuring multiple electron-withdrawing trifluoromethyl groups, which significantly enhance its stability and reactivity profile in demanding catalytic processes. This compound is engineered to provide superior performance in cross-coupling reactions by offering exceptional electron deficiency and steric bulk, leading to higher catalytic activity and selectivity. It is a critical component for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precision and reliability in their metal-catalyzed synthesis.

Application

• As a highly active ligand in palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Negishi, and Buchwald-Hartwig aminations.
• For the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs) where challenging bond formations are required.
• In the development of agrochemicals and fine chemicals that benefit from highly selective catalytic processes.
• As a key component in homogeneous catalysis research for creating novel catalytic systems with improved efficiency.
• For the preparation of electronic materials and organic semiconductors via metal-catalyzed polymerization or functionalization.
• In academic and industrial R&D laboratories focused on advancing synthetic methodology and organometallic chemistry.

Basic Information

Product Name	1,5-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Pentane
CAS No.	220185-42-2
Molecular Formula	C37H20F24P2
Molecular Weight	958.48 g/mol
Synonyms	1,5-Bis[bis(3,5-bis(trifluoromethyl)phenyl)phosphino]pentane; Dtpf-Pentane Ligand; 1,5-Bis(di(3,5-di(trifluoromethyl)phenyl)phosphino)pentane; Bis(3,5-di(trifluoromethyl)phenyl)phosphine Pentane Bridge; Dtpfpp; (3,5-(CF3)2C6H3)2P-(CH2)5-P(C6H3(CF3)2-3,5)2; Pentane-1,5-diylbis[bis(3,5-bis(trifluoromethyl)phenyl)phosphane]
EINECS	Contact for details

Quality Control

Our production of 1,5-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Pentane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, which is critical for catalytic performance. Each lot is characterized using advanced analytical techniques, including NMR and HPLC, to verify identity and assay. Certificates of Analysis (COA) detailing all relevant specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized and should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.