Description

1,3-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Propane is a specialized, high-value organophosphorus ligand characterized by its electron-deficient, sterically demanding bis(trifluoromethyl)phenyl groups. This compound matters for enabling highly efficient and selective transition metal-catalyzed reactions, particularly in the synthesis of complex pharmaceutical intermediates and advanced materials. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for challenging cross-coupling and hydrogenation reactions.

Application

• As a premium ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• For asymmetric hydrogenation catalysts in the production of chiral active pharmaceutical ingredients (APIs).
• In the development of novel catalysts for C-H activation and other challenging bond-forming transformations.
• As a key component in catalyst systems for fine chemical and agrochemical synthesis.
• For academic and industrial research into new catalytic methodologies.
• In the manufacture of electronic materials and OLED precursors where precise catalytic control is required.

Basic Information

Product Name	1,3-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Propane
CAS No.	220185-40-0
Molecular Formula	C35H18F24P2
Molecular Weight	884.44 g/mol
Synonyms	DTBPP; 1,3-Bis[bis(3,5-bis(trifluoromethyl)phenyl)phosphino]propane; Propane-1,3-diylbis[bis(3,5-bis(trifluoromethyl)phenyl)phosphane]; Bisphosphine Ligand DTBPP; Josiphos-type ligand analog; Electron-poor bisphosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our 1,3-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Propane is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including NMR (1H, 13C, 31P) and HPLC. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). Keep the container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.