Description

1,3-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Propane is a high-purity, sterically hindered bidentate phosphine ligand essential for advanced catalytic transformations. Its primary value lies in facilitating highly selective and efficient cross-coupling reactions, which are critical for constructing complex molecular architectures. This ligand is indispensable for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction stereochemistry and yield.

Application

• Homogeneous Catalysis: A key ligand for palladium and nickel-catalyzed cross-coupling reactions, including Suzuki, Heck, and Negishi couplings.
• Pharmaceutical Intermediates: Enables the synthesis of complex, chiral drug candidates and active pharmaceutical ingredients (APIs) with high enantioselectivity.
• Agrochemical Synthesis: Used in the production of advanced, high-performance herbicides, fungicides, and insecticides.
• Materials Science: Facilitates the creation of novel polymers and organic electronic materials through controlled polymerization.
• Asymmetric Hydrogenation: Serves as a chiral ligand for the asymmetric hydrogenation of prochiral olefins and ketones to produce enantiomerically pure compounds.
• Academic & Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel reaction pathways in process chemistry.

Basic Information

Product Name	1,3-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Propane
CAS No.	220185-36-4
Molecular Formula	C35H44P2
Molecular Weight	526.67 g/mol
Synonyms	1,3-Bis(di-3,5-xylylphosphino)propane; Dtxpp; 1,3-Propanediylbis[bis(3,5-dimethylphenyl)phosphine]; Bis(di-3,5-xylylphosphino)propane; 1,3-Bis[bis(3,5-dimethylphenyl)phosphanyl]propane; DTXPP Ligand; DTXPP
EINECS	Contact for details

Quality Control

Our production of 1,3-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Propane adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized using advanced analytical techniques, including NMR and HPLC, to verify identity, purity, and the absence of critical impurities like phosphine oxides. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its air-sensitive nature, containers should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Phosphine Oxide Content	≤ 2.0%
Melting Point	Contact for details
Solubility	Soluble in common organic solvents (Toluene, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.