Description

1,2-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Ethane is a specialized bidentate phosphine ligand of significant importance in advanced catalytic chemistry. Its primary value lies in its ability to form highly active and selective transition metal complexes, particularly for challenging cross-coupling and hydrogenation reactions. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over stereochemistry and reaction pathways.

Application

• Homogeneous Catalysis: As a key ligand in palladium- and rhodium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Asymmetric Synthesis: Enabling enantioselective hydrogenation and other transformations for the production of chiral intermediates.
• Pharmaceutical Intermediates: Facilitating the synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the catalytic synthesis of advanced herbicides, fungicides, and insecticides.
• Material Science Research: For the development of novel organometallic complexes and catalytic materials.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, flavors, and fragrances requiring high selectivity.

Basic Information

Product Name	1,2-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Ethane
CAS No.	220185-35-3
Molecular Formula	C36H40P2
Molecular Weight	534.64 g/mol
Synonyms	DTBM-PE; 1,2-Bis[bis(3,5-dimethylphenyl)phosphino]ethane; Ethane-1,2-diylbis[bis(3,5-dimethylphenyl)phosphane]; Bis(3,5-dimethylphenyl)phosphinoethane ligand; DTBMPE; 3,5-Xylyl-PE; 1,2-Bis(di-3,5-xylylphosphino)ethane
EINECS	Contact for details

Quality Control

Our 1,2-Bis[Bis(3,5-Dimethylphenyl)Phosphino]Ethane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive catalytic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; therefore, containers must be sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.