Description

(5S)-n-(tert-Butoxycarbonyl)-3,4,5,6-Tetrahydro-5-Phenyl-4(H)-1,4-Oxazin-2-One is a high-purity, chiral oxazinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a protected amino acid equivalent, enabling the stereoselective synthesis of complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for constructing peptide mimetics and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drugs and bioactive compounds.
• Peptidomimetic Synthesis: Used in the construction of non-peptide scaffolds that mimic peptide structure and function for drug discovery.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in reactions requiring high stereochemical control.
• API Development: Integral in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(5S)-n-(tert-Butoxycarbonyl)-3,4,5,6-Tetrahydro-5-Phenyl-4(H)-1,4-Oxazin-2-One
CAS No.	220077-24-7
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	(5S)-N-Boc-3,4,5,6-tetrahydro-5-phenyl-2H-1,4-oxazin-2-one; (5S)-5-Phenyl-3,4,5,6-tetrahydro-4H-1,4-oxazin-2-one, N-Boc derivative; tert-Butyl (5S)-2-oxo-5-phenyl-3,4,5,6-tetrahydro-2H-1,4-oxazine-4-carboxylate; (S)-N-Boc-5-phenylmorpholin-2-one; Boc-L-Phenylalanine-derived oxazinone; 4H-1,4-Oxazin-2-one, 3,4,5,6-tetrahydro-5-phenyl-, 4-(1,1-dimethylethoxy)carbonyl-, (5S)-
EINECS	Contact for details

Quality Control

Our (5S)-n-(tert-Butoxycarbonyl)-3,4,5,6-Tetrahydro-5-Phenyl-4(H)-1,4-Oxazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.