Description

2-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)Anisole is a specialized fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromo-tetrafluoroethoxy side chain and a methoxybenzene core, makes it a valuable precursor for constructing complex molecules with tailored electronic and physical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorinated segment can improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: The bromine atom acts as a handle for versatile palladium-catalyzed coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorine chemistry and the exploration of new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	2-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)Anisole
CAS No.	220004-17-1
Molecular Formula	C9H7BrF4O2
Molecular Weight	303.05 g/mol
Synonyms	1-(2-Bromo-1,1,2,2-tetrafluoroethoxy)-2-methoxybenzene; Anisole, 2-(2-bromo-1,1,2,2-tetrafluoroethoxy)-; 2-Methoxy-1-(2-bromo-1,1,2,2-tetrafluoroethoxy)benzene; 2-Bromo-1,1,2,2-tetrafluoroethyl 2-methoxyphenyl ether; 1-Bromo-1,1,2,2-tetrafluoro-2-(2-methoxyphenoxy)ethane
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)Anisole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.