Description

Benzene, 1,3,5-Trifluoro-2-Methoxy- (9Ci) is a fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and methoxy substitution pattern, which imparts specific electronic and steric properties crucial for developing novel materials and active pharmaceutical ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorine-containing functional groups into polymer backbones, enhancing chemical resistance and altering surface properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl systems for material science applications.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and reaction pathways in academic and industrial R&D settings.

Basic Information

Product Name	Benzene, 1,3,5-Trifluoro-2-Methoxy- (9Ci)
CAS No.	219998-30-8
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	1,3,5-Trifluoro-2-methoxybenzene; 2-Methoxy-1,3,5-trifluorobenzene; 1,3,5-Trifluoro-2-methoxybenzene (9CI); 2-Methoxy-1,3,5-trifluorobenzene; 1,3,5-Trifluoro-2-methoxy-benzene; 2-Methoxy-1,3,5-trifluoro-benzene; 1,3,5-Trifluoro-2-methoxybenzene (9CI)
EINECS	Contact for details

Quality Control

Our Benzene, 1,3,5-Trifluoro-2-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.