Description

α-Cgrp (29-37) (Rat) is a synthetic peptide fragment corresponding to amino acids 29-37 of the rat α-calcitonin gene-related peptide (α-CGRP). This high-purity reference standard is critical for neurological and cardiovascular research, enabling precise study of CGRP receptor interactions and signaling pathways. It is an essential tool for researchers and pharmaceutical developers in neuroscience, pharmacology, and drug discovery targeting migraine and cardiovascular disorders.

Application

• Biomedical Research: Used as a reference standard in receptor binding assays and functional studies of the CGRP pathway.
• Drug Discovery & Development: Serves as a critical tool for screening and characterizing potential CGRP receptor antagonists for migraine therapy.
• Neuroscience Studies: Applied in research investigating the role of CGRP in pain transmission, neurogenic inflammation, and vasodilation.
• Analytical Method Development: Utilized as a certified standard for calibrating HPLC, LC-MS, and other analytical systems in peptide quantification.
• Quality Control: Acts as a system suitability standard in the manufacturing and QC of related peptide-based pharmaceuticals.
• Academic Research: Supports fundamental research in universities and institutes studying cardiovascular regulation and sensory nerve function.

Basic Information

Product Name	α-Cgrp (29-37) (Rat)
CAS No.	219991-19-2
Molecular Formula	C47H78N14O13S
Molecular Weight	1079.3 g/mol
Synonyms	α-CGRP (29-37), rat; Calcitonin Gene-Related Peptide (29-37), rat alpha form; H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-NH2; rCGRPα (29-37); α-Calcitonin Gene-Related Peptide Fragment 29-37; CGRP (29-37) (Rat); α-Calcitonin Gene Related Peptide (29-37); Rat α-CGRP (29-37)
EINECS	Contact for details

Quality Control

Every batch of α-Cgrp (29-37) (Rat) is manufactured under strict quality systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically >95% by HPLC), and peptide content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.