Description

Methyl 5-Cyano-2-Iodobenzoate is a high-purity, multi-functional aromatic building block featuring both cyano and iodo substituents. This compound is valued for its versatility in advanced organic synthesis, enabling efficient cross-coupling reactions and further functional group transformations. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing biaryl or heteroaryl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the reactivity of the iodine atom for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form carbon-carbon bonds.
• Chemical Synthesis: The ester and nitrile groups provide handles for further hydrolysis, reduction, or cyclization to create diverse heterocyclic compounds.
• Laboratory Reagent: Employed in academic and industrial R&D settings as a standardized reagent for method development and scale-up chemistry.

Basic Information

Product Name	Methyl 5-Cyano-2-Iodobenzoate
CAS No.	219841-91-5
Molecular Formula	C9H6INO2
Molecular Weight	287.06 g/mol
Synonyms	2-Iodo-5-cyanobenzoic acid methyl ester; Methyl 2-iodo-5-cyanobenzoate; Benzoic acid, 5-cyano-2-iodo-, methyl ester; 5-Cyano-2-iodobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay (HPLC), related substances, and physical characteristics are available upon request. We adhere to a quality management system to guarantee supply reliability and product integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.