Description

(R)-n-Boc-2-(3'-Butenyl)Glycine CAS NO 219819-76-8 is a high-purity, non-proteinogenic amino acid derivative featuring a chiral center and a reactive terminal alkene group. This compound serves as a critical chiral building block in the synthesis of complex pharmaceutical intermediates and novel peptide-based therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce non-natural amino acid residues with a butenyl side chain.
• Chemical Biology Research: Employed as a building block for creating peptide libraries and probes to study protein-protein interactions and enzyme function.
• Prodrug Development: The Boc-protected amino acid functionality makes it suitable for designing prodrugs with improved pharmacokinetic properties.
• Material Science: Potential monomer for creating specialized polymers with unique chiral and functional properties.

Basic Information

Product Name	(R)-n-Boc-2-(3'-Butenyl)Glycine
CAS No.	219819-76-8
Molecular Formula	C₁₁H₁₉NO₄
Molecular Weight	229.27 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid; (R)-Boc-2-(3-Butenyl)glycine; (R)-N-Boc-2-(3-butenyl)glycine; (2R)-2-[(tert-Butoxycarbonyl)amino]pent-4-enoic Acid; (R)-2-(Boc-amino)pent-4-enoic acid; Boc-(R)-2-(3-butenyl)Gly-OH; (R)-N-(tert-Butoxycarbonyl)-2-(3-butenyl)glycine
EINECS	Contact for details

Quality Control

Our (R)-n-Boc-2-(3'-Butenyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.