Description

4-Ethoxy-1,1,1-Trifluorobutan-2-Ol is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both an ethoxy group and a trifluoromethyl-substituted alcohol, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its utility lies in introducing fluorine atoms and specific functional handles to modulate the bioavailability, metabolic stability, and binding affinity of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Fluorinated Surfactant & Lubricant Research: Acts as a building block for creating novel fluorosurfactants and high-performance lubricants with low surface tension and high stability.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and asymmetric synthesis routes.

Basic Information

Product Name	4-Ethoxy-1,1,1-Trifluorobutan-2-Ol
CAS No.	219777-03-4
Molecular Formula	C6H11F3O2
Molecular Weight	172.15 g/mol
Synonyms	4-Ethoxy-1,1,1-trifluoro-2-butanol; 1,1,1-Trifluoro-4-ethoxybutan-2-ol; 2-Butanol, 4-ethoxy-1,1,1-trifluoro-; 4-Ethoxy-1,1,1-trifluorobutan-2-ol; 4-Ethoxy-1,1,1-trifluoro-2-butanol; 219777-03-4; 4-Ethoxy-1,1,1-trifluoro-butane-2-ol
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-1,1,1-Trifluorobutan-2-Ol is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.