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R-2,2'-Dimethoxy-3,3'-Diphenyl-1,1'-Binaphthalene CAS NO 219757-68-3


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CAS No.:219757-68-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-2,2'-Dimethoxy-3,3'-Diphenyl-1,1'-Binaphthalene is a chiral, axially hindered binaphthyl derivative that serves as a sophisticated ligand precursor and building block in advanced organic synthesis. Its core value lies in its ability to induce high enantioselectivity in catalytic asymmetric reactions, which is critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

  • As a key chiral ligand precursor for asymmetric metal catalysis (e.g., hydrogenation, C-C bond formation).
  • Building block for the synthesis of novel chiral phosphine and phosphoramidite ligands.
  • Chiral auxiliary or resolving agent in the preparation of enantiomerically pure compounds.
  • Intermediate in the research and development of new active pharmaceutical ingredients (APIs).
  • Component in the synthesis of advanced materials with chiral optical properties.
  • Use in academic and industrial research for method development in asymmetric synthesis.

Basic Information

Item Details
Product Name R-2,2'-Dimethoxy-3,3'-Diphenyl-1,1'-Binaphthalene
CAS No. 219757-68-3
Molecular Formula C34H26O2
Molecular Weight 466.57 g/mol
Synonyms (R)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthalene; (R)-3,3'-Diphenyl-2,2'-dimethoxy-1,1'-binaphthyl; (R)-2,2'-Dimethoxy-3,3'-diphenyl-[1,1'-binaphthalene]; R-DMDPB; (R)-DMDPB; (R)-2,2'-Dimethoxy-3,3'-diphenylbinaphthyl; (R)-3,3'-Diphenyl-2,2'-dimethoxy-1,1'-binaphthalene; (R)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthyl
EINECS Contact for details

Quality Control

Our R-2,2'-Dimethoxy-3,3'-Diphenyl-1,1'-Binaphthalene is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) with full specifications are provided to guarantee compliance with your research and process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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