Description

Visilizumab is a humanized monoclonal antibody designed for targeted immunomodulation. This high-purity biological agent is critical for research and development in advanced therapeutic applications, offering precise targeting capabilities. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on immunology and novel treatment modalities. Our supply ensures consistent quality and reliability for your most demanding projects.

Application

• Immunological Research: A key reagent for studying T-cell mediated immune responses and signaling pathways.
• Therapeutic Development: Serves as a reference standard or active pharmaceutical ingredient (API) in the development of novel immunotherapies.
• Biomarker Studies: Used in assays to investigate specific cell surface targets and their role in disease mechanisms.
• Preclinical Evaluation: Essential for in vitro and in vivo studies to assess efficacy, pharmacokinetics, and safety profiles.
• Process Development & Scale-up: Supports downstream manufacturing process optimization for biologic production.
• Quality Control & Analytical Testing: Acts as a system suitability standard in analytical method development and validation (e.g., HPLC, ELISA).

Basic Information

Product Name	Visilizumab
CAS No.	219716-33-3
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Contact for details)
Synonyms	Nuvion; HuM291; Anti-CD3 Monoclonal Antibody (Humanized); Monoclonal Antibody to CD3 Epsilon; Immunosuppressive Monoclonal Antibody
EINECS	Contact for details

Quality Control

Our Visilizumab is manufactured and tested under a rigorous quality management system. Each batch is subjected to comprehensive analytical characterization to ensure identity, purity, potency, and consistency. Certificates of Analysis (COA) documenting specifications such as purity (by SEC-HPLC and CE-SDS), endotoxin levels, sterility, and biological activity are available upon request, supporting compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled humidity conditions upon opening.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/CE)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content	≥ 1.0 mg/mL (or as per COA)
Endotoxin	< 1.0 EU/mg
Biological Activity (Cell-based assay)	Conforms to reference (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.