Description

L-Serine, o-(Cyclohexylmethyl)-n-[(1,1-Dimethylethoxy)Carbonyl]- is a protected serine derivative, a crucial building block in advanced organic synthesis and peptide chemistry. Its primary value lies in providing a chiral, functionalized backbone with orthogonal protecting groups, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially protease inhibitors and other peptide-mimetic pharmaceuticals.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate serine residues with specific side-chain protection, critical for creating custom peptides and peptidomimetics.
• Bioconjugation & Linker Chemistry: Serves as a functional handle for creating bioconjugates or attaching payloads in antibody-drug conjugate (ADC) research and prodrug development.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes, enzyme substrates, and other tools for studying biological pathways and protein function.
• Agrochemical Research: Acts as a precursor in the development of novel, biologically active compounds for crop protection.
• Material Science: Potential use in the synthesis of specialized polymers and biomaterials where amino acid-derived monomers are required.

Basic Information

Product Name	L-Serine, o-(Cyclohexylmethyl)-n-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	219626-93-4
Molecular Formula	C15H27NO5
Molecular Weight	301.38 g/mol
Synonyms	N-Boc-O-cyclohexylmethyl-L-serine; Boc-Ser(Chm)-OH; tert-Butyl N-[(2S)-2-hydroxy-3-(cyclohexylmethoxy)propyl]carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-3-(cyclohexylmethoxy)propanoic acid; N-(tert-Butoxycarbonyl)-O-cyclohexylmethyl-L-serine; Boc-L-Ser(Chm)-OH; O-Cyclohexylmethyl-N-Boc-L-serine
EINECS	Contact for details

Quality Control

Our L-Serine, o-(Cyclohexylmethyl)-n-[(1,1-Dimethylethoxy)Carbonyl]- is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.