Description

n-Butyl L-Z-Valinamide is a specialized chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex peptide mimetics and pharmaceutical intermediates with high stereochemical fidelity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptidomimetic Research: Used in medicinal chemistry to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a building block in stereoselective reactions to introduce the valine moiety into complex molecular architectures.
• Protease Inhibitor Development: Employed in the research and development of enzyme inhibitors targeting various proteases.
• Chemical Biology Probes: Utilized for the preparation of labeled or modified peptides used as tools in biochemical and cellular studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom compounds for clients.

Basic Information

Product Name	n-Butyl L-Z-Valinamide
CAS No.	219323-42-9
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	L-Valine, N-[(benzyloxy)carbonyl]-, butylamide; Z-L-Val-NH-n-Bu; Nα-Carbobenzoxy-L-valine n-butylamide; (S)-2-((Benzyloxycarbonyl)amino)-3-methylbutanamide, N-butyl-; Cbz-L-Val-NH-Bu; N-Cbz-L-valinamide n-butyl; Benzyl (S)-(1-(butylamino)-3-methyl-1-oxobutan-2-yl)carbamate; Nα-Z-L-Valine butylamide
EINECS	Contact for details

Quality Control

Our n-Butyl L-Z-Valinamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.