Description

Bz-Gly-4-Thia-Lys-Oh CAS NO 219137-68-5 is a specialized protected amino acid derivative, specifically a benzoyl-glycine conjugate of a thialysine analog. This compound serves as a critical building block in advanced peptide synthesis, offering precise control over molecular structure and function. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic peptides and investigating metabolic pathways.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific structural motifs.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or affinity probes used in biochemical and diagnostic research.
• Metabolism Studies: Utilized as a synthetic analog in studies of lysine metabolism and related enzymatic processes.
• Chemical Biology Tool: Employed to modulate peptide properties and study structure-activity relationships (SAR) in drug discovery projects.

Basic Information

Product Name	Bz-Gly-4-Thia-Lys-Oh
CAS No.	219137-68-5
Molecular Formula	C14H19N3O4S
Molecular Weight	325.38 g/mol
Synonyms	N2-Benzoyl-N6-[(tert-butoxy)carbonyl]-L-4-thialysine; BOC-4-Thia-Lys(Bz)-OH; (2S)-6-[(tert-Butoxycarbonyl)amino]-2-(benzoylamino)-5-thiahexanoic acid; Benzoyl-Glycine-4-Thia-Lysine-OH; Bz-Gly-Thia-Lys(Boc)-OH; Nα-Benzoyl-Nε-Boc-4-thia-L-lysine; Protected 4-Thialysine derivative
EINECS	Contact for details

Quality Control

Our Bz-Gly-4-Thia-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.