Description

Benzeneacetonitrile, 2-Amino-4-Fluoro- (9Ci) is a specialized fluorinated aromatic nitrile building block. This compound is valued for its bifunctional reactivity, featuring both an amino group and a nitrile moiety on a fluorinated benzene ring, enabling its use in sophisticated synthetic pathways. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from the introduction of fluorine atoms.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for creating fluorescent tags or activity-based probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Benzeneacetonitrile, 2-Amino-4-Fluoro- (9Ci)
CAS No.	218961-89-8
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	2-Amino-4-fluorobenzeneacetonitrile; 4-Fluoro-2-aminobenzyl cyanide; 2-Amino-4-fluorophenylacetonitrile; (2-Amino-4-fluorophenyl)acetonitrile; 2-Cyano-5-fluoroaniline; 5-Fluoro-2-aminobenzyl cyanide; 2-Amino-α-cyano-4-fluorotoluene; 4-Fluoroanthranilonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-fluorobenzeneacetonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.