Description

Aspartic Acid(Otbu)-Allyl Ester Hcl is a protected amino acid derivative widely used as a key building block in organic synthesis and peptide chemistry. This compound is valued for its dual functionality, featuring an acid-labile tert-butyl ester group and a versatile allyl ester group, enabling selective deprotection and further chemical modifications. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel peptides, prodrugs, and other bioactive molecules.

Application

• Peptide Synthesis: Serves as a crucial protected aspartic acid residue in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrug candidates.
• Bioconjugation: The allyl ester group provides a handle for site-specific conjugation with thiols via click chemistry or other coupling reactions.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides and molecular probes for biochemical and diagnostic research.
• Material Science: Acts as a monomer or cross-linker precursor for designing functional polymers and biomaterials.

Basic Information

Product Name	Aspartic Acid(Otbu)-Allyl Ester Hcl
CAS No.	218938-66-0
Molecular Formula	C11H20ClNO4
Molecular Weight	265.73 g/mol
Synonyms	H-Asp(OtBu)-OAllyl·HCl; L-Aspartic acid 4-(1,1-dimethylethyl) ester 1-(2-propen-1-yl) ester hydrochloride; Allyl L-aspartate tert-butyl ester hydrochloride; Fmoc-Asp(OtBu)-OH Allyl Ester; Boc-Asp(OtBu)-OAllyl; Aspartic acid β-tert-butyl ester α-allyl ester hydrochloride; (S)-2-((Allyloxy)carbonylamino)-4-((tert-butoxy)carbonyl)butanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Aspartic Acid(Otbu)-Allyl Ester Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.