Description

Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy- (9Ci) is a high-purity, protected amino acid derivative of significant interest in advanced organic synthesis. This compound is valued for its role as a key chiral building block, enabling the construction of complex molecules with precise stereochemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates and complex bioactive molecules.
• Peptide Chemistry: Used in the preparation of non-natural amino acids and for the side-chain protection of aspartic acid or glutamic acid analogues during solid-phase or solution-phase peptide synthesis.
• Chemical Research & Development: Employed as a standardized starting material or reference standard in method development and route scouting for new chemical entities.
• Agrochemical Synthesis: Can be utilized in the research and development of advanced herbicides, fungicides, or plant growth regulators requiring specific chiral centers.
• Academic Research: A valuable reagent for universities and research institutes studying asymmetric synthesis, reaction mechanisms, and molecular design.

Basic Information

Product Name	Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy- (9Ci)
CAS No.	218916-64-4
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Synonyms	N-Boc-L-β-Hydroxyaspartic Acid 1-tert-Butyl Ester; (2S,3R)-3-[(tert-Butoxycarbonyl)amino]-2-hydroxybutanedioic acid 1-tert-butyl ester; Nα-Boc-3-hydroxy-L-aspartic acid α-tert-butyl ester; Boc-Asp(OH)(OtBu)-OH; Boc-L-β-hydroxyaspartic acid α-tert-butyl ester; 3-[(tert-Butoxycarbonyl)amino]-2-hydroxy-succinic acid 1-tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.