Description

n-Docosahexaenoic Sphingomyelin is a specialized, high-purity sphingolipid where the fatty acid moiety is docosahexaenoic acid (DHA), a critical ω-3 fatty acid. This unique molecular structure is essential for advanced research and development in lipidomics, membrane biophysics, and the formulation of next-generation nutraceuticals and pharmaceuticals. It is particularly valuable for scientists and product developers in the life sciences, pharmaceutical, and high-end nutritional supplement industries seeking to investigate or leverage the specific biological functions of DHA within cellular membrane structures.

Application

• Biomedical Research: As a critical standard and reagent in lipidomics research, membrane fluidity studies, and investigations into lipid rafts and cell signaling pathways.
• Pharmaceutical Development: Used in the formulation of advanced drug delivery systems, including liposomes and lipid nanoparticles (LNPs), where DHA-conjugated lipids can enhance targeting and bioavailability.
• Nutraceutical Innovation: A key ingredient in the development of high-purity, structurally-defined supplements aimed at supporting brain health, cognitive function, and anti-inflammatory responses.
• Cosmeceuticals: Incorporated into premium skincare formulations for its potential role in supporting skin barrier function and cellular membrane integrity.
• Analytical Standards: Serves as a certified reference material (CRM) for the qualitative and quantitative analysis of complex sphingolipid mixtures via HPLC, LC-MS, and other analytical techniques.
• Cell Culture & Biochemistry: Used to supplement cell culture media or create model membranes to study the effects of specific lipid species on cellular behavior and metabolism.

Basic Information

Product Name	n-Docosahexaenoic Sphingomyelin
CAS No.	218608-41-4
Molecular Formula	C51H94N2O9P
Molecular Weight	919.27 g/mol
Synonyms	DHA-Sphingomyelin; SM(DHA); N-Docosahexaenoyl Sphingosyl Phosphocholine; (2S,3R,4E)-2-Docosahexaenoylamino-4-octadecene-1,3-diol 1-Phosphocholine; Sphingomyelin (DHA); 1-Phosphocholine-2-(docosahexaenoylamino)-4-octadecene-1,3-diol; DHA-Ceramide Phosphocholine; N-(4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoyl)-sphing-4-enine-1-phosphocholine
EINECS	Contact for details

Quality Control

Our n-Docosahexaenoic Sphingomyelin is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with relevant research and cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.