Description

Brain Derived Neurotrophic Factor, Human is a crucial neurotrophic protein that supports the survival, differentiation, and growth of neurons. Its primary value lies in advanced neuroscience research and the development of novel therapeutic strategies for neurological disorders. This high-purity protein is essential for researchers and developers in pharmaceutical R&D, academic institutions, and biotechnology companies focused on neurodegenerative diseases and neural repair.

Application

• Neuroscience Research: Fundamental studies on neuronal survival, differentiation, synaptic plasticity, and neurogenesis.
• Drug Discovery & Development: Target validation and screening for novel therapeutics targeting neurodegenerative conditions like Alzheimer's and Parkinson's disease.
• Cell Culture & In Vitro Models: Essential component in media for culturing primary neurons and stem cell-derived neural cells.
• Biomarker Studies: Investigation of BDNF levels and signaling pathways in various neurological and psychiatric disorders.
• Regenerative Medicine: Research into nerve regeneration and repair following injury or disease.
• Diagnostic Development: Production of antibodies and calibration standards for BDNF detection assays (e.g., ELISA).

Basic Information

Product Name	Brain Derived Neurotrophic Factor, Human
CAS No.	218441-99-7
Molecular Formula	C795H1227N213O232S9
Molecular Weight	Approx. 27.8 kDa (monomer)
Synonyms	BDNF; Brain-Derived Neurotrophic Factor; Abrineurin; Brain-Derived Neurotrophic Factor Precursor; BDNF, Human; Recombinant Human BDNF; Neurotrophin-2; NT-2; Brain-Derived Neurotrophic Factor (Human); BDNF Protein, Human
EINECS	Contact for details

Quality Control

Our Brain Derived Neurotrophic Factor, Human is produced under stringent conditions to ensure high biological activity and exceptional purity. Each batch undergoes comprehensive analytical testing, including SDS-PAGE, HPLC, and bioactivity assays, to guarantee consistency and performance. Certificates of Analysis (COA) detailing purity, endotoxin levels, and biological activity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Determined by cell-based proliferation assay
Solubility	Soluble in water or PBS
Identification (Mass Spec)	Consistent with theoretical molecular weight

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.