Description

L-Dopa-4'-Sulfate CAS NO 217657-34-6 is a sulfated derivative of the important biochemical precursor L-Dopa (Levodopa). This specialized compound is of significant interest in pharmaceutical research and development, particularly for its potential as a metabolite or prodrug with altered pharmacokinetic properties. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector. Target industries include pharmaceutical R&D, analytical laboratories, and fine chemical synthesis.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of L-Dopa metabolites in analytical methods like HPLC and LC-MS.
• Biochemical Research: Employed in studies investigating the metabolism, transport, and stability of Levodopa and its conjugates.
• Prodrug Development: Investigated as a potential prodrug candidate to modify the solubility, bioavailability, or blood-brain barrier penetration of L-Dopa.
• Enzyme Substrate: Serves as a specific substrate for studying sulfatase enzyme activity and kinetics in vitro.
• Metabolite Synthesis: Acts as a key synthetic intermediate for preparing other sulfate-conjugated metabolites for research purposes.
• Diagnostic Agent Development: Explored in the development of diagnostic assays and tools related to Parkinson's disease and dopamine metabolism.

Basic Information

Product Name	L-Dopa-4'-Sulfate
CAS No.	217657-34-6
Molecular Formula	C9H11NO7S
Molecular Weight	277.25 g/mol
Synonyms	L-DOPA 4'-Sulfate; Levodopa 4'-Sulfate; (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-3-oxopropanoic acid 4'-sulfate; 3-Hydroxy-L-tyrosine 4'-sulfate; L-3,4-Dihydroxyphenylalanine 4'-sulfate; L-(-)-Dopa 4'-Sulfate; 4'-O-Sulfo-L-DOPA
EINECS	Contact for details

Quality Control

Our L-Dopa-4'-Sulfate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.