Description

Ethyl 2-Hydroxy-2-(Trifluoromethyl)-4-Methylpent-4-Enoate 97 is a high-purity fluorinated building block essential for advanced organic synthesis. This compound matters because its unique trifluoromethyl and hydroxyl functional groups enable the precise introduction of fluorine atoms, a critical strategy for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where the CF3 group enhances efficacy and environmental profile.
• Fluorine Chemistry Research: Serves as a versatile precursor for studying new fluorination reactions and creating complex fluorinated scaffolds in academic and industrial labs.
• Material Science: Potential building block for specialty polymers and liquid crystals where fluorine content improves thermal stability and optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke fluorinated compounds for client projects.

Basic Information

Product Name	Ethyl 2-Hydroxy-2-(Trifluoromethyl)-4-Methylpent-4-Enoate 97
CAS No.	217195-91-0
Molecular Formula	C10H15F3O3
Molecular Weight	240.22 g/mol
Synonyms	Ethyl 2-Hydroxy-2-(trifluoromethyl)-4-methyl-4-pentenoate; 4-Methyl-4-pentenoic acid, 2-hydroxy-2-(trifluoromethyl)-, ethyl ester; 2-Hydroxy-2-(trifluoromethyl)-4-methyl-4-pentenoic Acid Ethyl Ester; Ethyl 2-Hydroxy-2-(trifluoromethyl)-4-methylpent-4-enoate; 217195-91-0; Trifluoromethylated Hydroxy Ester; Fluorinated Hydroxy Ester Building Block
EINECS	Contact for details

Quality Control

Our Ethyl 2-Hydroxy-2-(Trifluoromethyl)-4-Methylpent-4-Enoate 97 is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the minimum 97% purity and consistent impurity profile required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.