Description

Ethyl 5,5,5-Trifluoropentanoate is a high-purity fluorinated ester building block, valued for its role in introducing the trifluoromethyl group into complex molecular architectures. This compound is essential for synthetic chemists developing advanced materials and active pharmaceutical ingredients (APIs) where fluorine substitution is critical for modulating properties like metabolic stability, lipophilicity, and bioavailability. It serves as a key intermediate for research and production in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring a trifluoromethylated side chain to enhance biological activity and pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated organic compounds for electronic displays and lighting applications.
• Polymer Modification: Employed to incorporate fluorine into polymer backbones, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and other catalytic processes for constructing complex fluorinated molecules in R&D settings.

Basic Information

Product Name	Ethyl 5,5,5-Trifluoropentanoate
CAS No.	217186-74-8
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	5,5,5-Trifluoropentanoic Acid Ethyl Ester; Ethyl 5,5,5-Trifluorovalerate; Ethyl β,β,β-Trifluoropentanoate; 217186-74-8; Ethyl 5,5,5-Trifluorovalerate; Valeric acid, 5,5,5-trifluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5,5,5-Trifluoropentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.375 - 1.385
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.