Description

(R,R)-1,1'-Bis[Dinaphtho[1,2-D,1,2F][1,3,2]Dioxaphosphepin-8-Yl]Ferrocene is a highly specialized, chiral phosphine ligand used in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in critical synthetic transformations, enabling the production of single-enantiomer compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones, crucial for synthesizing chiral pharmaceutical intermediates.
• Asymmetric C-C Bond Formation: Employed in reactions such as cross-coupling, allylic alkylation, and conjugate addition to construct complex chiral molecules with high fidelity.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Facilitates the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Flavor/Fragrance Production: Enables the synthesis of high-value chiral compounds used in specialty chemicals, flavors, and aromas.
• Academic and Industrial R&D: A valuable tool for methodology development and exploring new catalytic asymmetric processes in both academic and corporate research laboratories.

Basic Information

Item	Details
Product Name	(R,R)-1,1'-Bis[Dinaphtho[1,2-D,1,2F][1,3,2]Dioxaphosphepin-8-Yl]Ferrocene
CAS No.	217175-10-5
Molecular Formula	C54H36FeO4P2
Molecular Weight	858.64 g/mol
Synonyms	(R,R)-BINAP-Ferrocene; (R,R)-BINAP-Fc; (R,R)-2,2'-Bis(diphenylphosphino)-1,1'-bis(naphtho[2,1-d][1,3,2]dioxaphosphepin-8-yl)ferrocene; (R,R)-BINAP-Ferrocenyl Diphosphine; (R,R)-BINAP-Ferrocene Ligand; (R,R)-BINAP-Ferrocenylphosphine; Josiphos-type ligand analog; Chiral ferrocenylphosphine ligand
EINECS	Contact for details

Quality Control

Our production of (R,R)-1,1'-Bis[Dinaphtho[1,2-D,1,2F][1,3,2]Dioxaphosphepin-8-Yl]Ferrocene adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity verification and metal content analysis. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.