Description

D-Erythro-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is a high-purity, specialty chiral building block of significant interest in advanced organic synthesis. This compound is valued for its defined stereochemistry and protected amine functionality, which provides a versatile handle for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in nucleoside and carbohydrate-based therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where specific spatial orientation is critical for bioactivity.
• Peptidomimetic Research: Serves as a constrained scaffold or backbone component in the design of peptide mimics for drug discovery.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and mechanisms.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting studies in synthetic methodology and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP or non-GMP conditions.

Basic Information

Product Name	D-Erythro-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-
CAS No.	217089-27-5
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3,4,5-trideoxy-D-erythro-pentitol; (3R,4S)-3-[(tert-Butoxycarbonyl)amino]pentane-1,2,4-triol; 3-Amino-3,4,5-trideoxy-D-erythro-pentitol, N-Boc derivative; N-Boc-3-amino-3,4,5-trideoxy-D-erythro-pentitol; Boc-D-erythro-3-aminopentitol; 217089-27-5; tert-Butyl ((3R,4S)-1,2,4-trihydroxypentan-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our production of D-Erythro-Pentitol, 3,4,5-Trideoxy-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and impurity profiles is provided with every shipment. We support development and commercial projects with material suitable for research use, non-GMP, or cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.