Description

2-Butynamide,n-[(3S)-Tetrahydro-2-Oxo-3-Furanyl]-(9Ci) is a specialized chiral building block and pharmaceutical intermediate of significant interest in synthetic organic chemistry. Its core value lies in its unique molecular architecture, featuring a butynamide moiety fused with a (3S)-tetrahydro-2-oxo-3-furanyl group, which makes it a versatile precursor for complex molecule synthesis. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly those exploring novel heterocyclic compounds and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) or anti-infective agents.
• Organic Synthesis Building Block: Used in advanced organic reactions, including Sonogashira coupling, click chemistry, and other cross-coupling methodologies to construct complex molecular frameworks.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and study of new asymmetric catalytic processes.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies to explore new chemical spaces for biological activity.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	2-Butynamide,n-[(3S)-Tetrahydro-2-Oxo-3-Furanyl]-(9Ci)
CAS No.	216596-79-1
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	(3S)-3-(But-2-ynamido)dihydrofuran-2(3H)-one; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-2-butynamide; (S)-3-(But-2-ynoylamino)dihydrofuran-2(3H)-one; (S)-3-(But-2-ynamido)dihydrofuran-2(3H)-one; 2-Butynamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]- (9CI); (S)-3-(But-2-ynoylamino)tetrahydrofuran-2-one; 216596-79-1
EINECS	Contact for details

Quality Control

Our 2-Butynamide,n-[(3S)-Tetrahydro-2-Oxo-3-Furanyl]-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.