Description

Carbamic Acid, n-[(1R)-1-(Hydroxymethyl)-2-[(Triphenylmethyl)Thio]Ethyl]-, 9H-Fluoren-9-Ylmethyl Ester is a sophisticated, optically active building block used in advanced organic synthesis. This compound is critical for the controlled assembly of complex molecules, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in peptide chemistry, prodrug development, and the synthesis of targeted therapeutic agents.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used as a building block for the development of protease inhibitors and other bioactive peptide mimetics.
• Prodrug Design: Employed in creating targeted drug delivery systems where specific functional groups require protection.
• Chemical Biology: Acts as a tool compound for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (1R) stereochemistry for constructing stereochemically complex molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing custom APIs and advanced intermediates.

Basic Information

Product Name	Carbamic Acid, n-[(1R)-1-(Hydroxymethyl)-2-[(Triphenylmethyl)Thio]Ethyl]-, 9H-Fluoren-9-Ylmethyl Ester
CAS No.	215954-72-6
Molecular Formula	C38H33NO3S
Molecular Weight	583.74 g/mol
Synonyms	Fmoc-Cys(Trt)-OH; Fmoc-Cys(Trt); Fmoc-S-trityl-L-cysteine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-cysteine; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tritylthio)propanoic acid; N-α-Fmoc-S-trityl-L-cysteine; Fmoc-Cys(Trt)-OH; Fmoc-L-Cys(Trt)-OH
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[(1R)-1-(Hydroxymethyl)-2-[(Triphenylmethyl)Thio]Ethyl]-, 9H-Fluoren-9-Ylmethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency for critical research and development. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards of pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.