Description

Biotinyl-ε-Aminocaproyl-Glu-Pro-Gln-Tyr(Po3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-Oh is a synthetic, biotinylated peptide sequence containing a phosphorylated tyrosine residue. This compound is a critical biochemical tool for studying protein-protein interactions, kinase activity, and signal transduction pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, biomarker discovery, and high-throughput screening for drug development.

Application

• Biochemical Research: As a specific substrate or capture agent in kinase activity assays and phosphorylation studies.
• Proteomics & Biomarker Discovery: Used in affinity purification and mass spectrometry to isolate and identify interacting proteins or phospho-specific binding partners.
• Diagnostic Development: Serves as a key component in the development of ELISA and other immunoassays for detecting specific antibodies or analytes.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify potential inhibitors or modulators of specific enzymatic targets.
• Cell Signaling Studies: Used to investigate intracellular signaling cascades involving tyrosine phosphorylation events.
• Antibody Production & Validation: Acts as an immunogen or a critical antigen for generating and validating phospho-specific antibodies.

Basic Information

Product Name	Biotinyl-ε-Aminocaproyl-Glu-Pro-Gln-Tyr(Po3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-Oh
CAS No.	215876-01-0
Molecular Formula	C95H141N19O30PS
Molecular Weight	2073.3 g/mol
Synonyms	Biotin-ε-Ahx-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH; Biotinyl-6-Aminocaproyl-Glu-Pro-Gln-phosphoTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu; Biotin-Ahx-EPQ-pY-EEIPIYL-OH; Biotinylated Phosphopeptide; pTyr Peptide Substrate; Biotin-EPQpYEEIPIYL; Biotin-Ahx-EPQpYEEIPIYL-OH
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Biotinyl-ε-Aminocaproyl-Glu-Pro-Gln-Tyr(Po3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-Oh is characterized by advanced analytical techniques including HPLC and MS to confirm identity, purity, and correct phosphorylation. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Single Phosphorylation (MS/MS)	Confirmed on specified tyrosine
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.