Description

2-(4-Bromo-3-Methylphenyl)Acetonitrile is a versatile brominated aromatic nitrile building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the bromine and nitrile groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its aromatic core and modifiable functional groups.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(4-Bromo-3-Methylphenyl)Acetonitrile
CAS No.	215800-25-2
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	(4-Bromo-3-methylphenyl)acetonitrile; 4'-Bromo-3'-methylphenylacetonitrile; 2-(4-Bromo-3-methylphenyl)ethanenitrile; 4-Bromo-3-methylbenzyl cyanide; α-Cyano-4-bromo-3-methyltoluene; p-Bromo-m-tolylacetonitrile; 1-(4-Bromo-3-methylphenyl)-2-cyanoethane; 215800-25-2
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-3-Methylphenyl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.