Description

3-(2-tert-Butoxycarbonylamino-Ethylcarbamoyl)-Acrylic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound serves as a critical building block for the controlled introduction of functionalized acrylic acid moieties into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for peptide-mimetic drugs and specialized polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Peptidomimetic Chemistry: Used to incorporate a carboxylic acid functional group with a protected amine side chain, mimicking natural amino acids in drug design.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Polymer Science: Monomer or co-monomer for synthesizing specialty acrylic polymers with pendant amine functionality for coatings or hydrogels.
• Bioconjugation: Useful linker molecule for attaching peptides, drugs, or labels to surfaces, nanoparticles, or other biomolecules.
• Chemical Biology Probes: Serves as a precursor for activity-based probes targeting specific enzymes or biological pathways.

Basic Information

Product Name	3-(2-tert-Butoxycarbonylamino-Ethylcarbamoyl)-Acrylic Acid
CAS No.	215654-55-0
Molecular Formula	C11H18N2O5
Molecular Weight	258.27 g/mol
Synonyms	Boc-AEEA-Acrylic Acid; 2-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)carbamoyl]acrylic Acid; N-(2-{[(tert-Butoxy)carbonyl]amino}ethyl)-2-carboxyacrylamide; Acrylic acid, 3-[(2-[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]-3-oxo-; (2E)-4-Oxo-4-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]but-2-enoic Acid; Boc-NH-(CH2)2-NH-CO-CH=CH-COOH
EINECS	Contact for details

Quality Control

Our 3-(2-tert-Butoxycarbonylamino-Ethylcarbamoyl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent decomposition. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.