Description

3-(4-Amino-Imidazol-1-Yl)-Propionitrile 2Hcl is a high-purity, specialized chemical building block primarily used in advanced pharmaceutical synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex heterocyclic APIs and investigational new drugs.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Biochemical Probe Development: Useful for creating labeled compounds and probes for biochemical and cellular assays.

Basic Information

Product Name	3-(4-Amino-Imidazol-1-Yl)-Propionitrile 2Hcl
CAS No.	215099-39-1
Molecular Formula	C6H9N5 · 2HCl
Molecular Weight	240.10 g/mol (as free base: 151.17 g/mol)
Synonyms	3-(4-Amino-1H-imidazol-1-yl)propanenitrile dihydrochloride; 1-(2-Cyanoethyl)-4-aminoimidazole dihydrochloride; 4-Amino-1-(2-cyanoethyl)imidazole dihydrochloride; 3-(4-Aminoimidazol-1-yl)propionitrile hydrochloride (2:1); AI1P Dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-Imidazol-1-Yl)-Propionitrile 2Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.