Description

4-Pentenamide, 3-(Hydroxymethyl)-n-[(1S)-1-(1-Naphthalenyl)Ethyl]-, (3S)- is a chiral, non-racemic organic compound featuring a pentenamide backbone substituted with hydroxymethyl and naphthalene-based groups. This molecule matters as a sophisticated pharmaceutical intermediate or chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the multi-step synthesis of novel therapeutic agents.
• Asymmetric Synthesis: Serves as a building block for constructing complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential API candidates.
• Catalyst Ligand Synthesis: Potential precursor for developing novel chiral ligands used in catalytic asymmetric reactions.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	4-Pentenamide, 3-(Hydroxymethyl)-n-[(1S)-1-(1-Naphthalenyl)Ethyl]-, (3S)-
CAS No.	214976-90-6
Molecular Formula	C₁₈H₂₁NO₂
Molecular Weight	283.37 g/mol
Synonyms	(3S)-3-(Hydroxymethyl)-N-[(1S)-1-(naphthalen-1-yl)ethyl]pent-4-enamide; (3S)-3-(Hydroxymethyl)-N-[(1S)-1-(1-naphthyl)ethyl]-4-pentenamide; (S)-N-((S)-1-(Naphthalen-1-yl)ethyl)-3-(hydroxymethyl)pent-4-enamide; 214976-90-6; Chiral Pentenamide Derivative; Naphthyl Ethyl Pentenamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and impurities are available upon request. Production can adhere to cGMP guidelines for pharmaceutical applications as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.