Description

(E)-2-Cyano-3-Hydroxy-n-[4-(Trifluoromethyl)Phenyl]But-2-Enamide is a high-value, specialized organic intermediate featuring a cyano-enamide core structure with a trifluoromethylphenyl substituent. This compound is critical for its role as a key building block in the synthesis of advanced pharmaceutical compounds and functional materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging the biological activity of the enamide and trifluoromethyl groups.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Functions as a versatile synthon in organic chemistry for constructing complex heterocycles and other sophisticated molecular architectures.
• Biochemical Probe Development: Utilized in medicinal chemistry to create tool compounds for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	(E)-2-Cyano-3-Hydroxy-n-[4-(Trifluoromethyl)Phenyl]But-2-Enamide
CAS No.	214782-56-6
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	(E)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide; 2-Butenamide, 2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-, (2E)-; 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide; (E)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)crotonamide; 4-(Trifluoromethyl)phenyl cyano-hydroxybutenamide; CTF-Enamide Intermediate; Trifluoromethyl Phenyl Enamide Derivative
EINECS	Contact for details

Quality Control

Our production of (E)-2-Cyano-3-Hydroxy-n-[4-(Trifluoromethyl)Phenyl]But-2-Enamide adheres to stringent in-process controls and final batch release testing to ensure consistent purity and identity. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.