Description

Boc-Dap(Dnp)-Oh is a specialized, protected amino acid derivative used as a critical building block in peptide synthesis. This compound matters for its role in introducing the unique diaminopropionic acid (Dap) moiety into peptide chains while providing orthogonal protection for the side chain amine and the α-carboxyl group. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of diaminopropionic acid residues into custom peptide sequences.
• Pharmaceutical Research: Used in the development of peptide drugs, hormone analogs, and enzyme inhibitors where precise side-chain functionality is required.
• Bioconjugation & Linker Chemistry: Serves as a versatile scaffold for creating peptide-drug conjugates or attaching peptides to surfaces, labels, or other biomolecules.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Antibiotic & Antimicrobial Peptide Development: Useful in constructing peptides with modified backbones or charged side chains to enhance stability and activity.

Basic Information

Product Name	Boc-Dap(Dnp)-Oh
CAS No.	214750-67-1
Molecular Formula	C₁₄H₁₈N₄O₇
Molecular Weight	354.32 g/mol
Synonyms	Boc-Dap(Dnp)-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-[(2,4-dinitrophenyl)amino]propanoic acid; Nα-Boc-Nβ-(2,4-dinitrophenyl)-L-diaminopropionic acid; Boc-L-Dap(Dnp)-OH; Boc-Dap(Dnp); tert-Butyloxycarbonyl-Dap(Dnp)-OH; Boc-Dap(Dnp)-OH CAS 214750-67-1; Nα-Boc-Nβ-Dnp-L-2,3-diaminopropionic acid
EINECS	Contact for details

Quality Control

Our Boc-Dap(Dnp)-Oh is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.