Description

Carbamic Acid, [(2R)-2-Hydroxypentyl]-, 1,1-Dimethylethyl Ester (9Ci) is a chiral, protected amino alcohol derivative of significant value in advanced organic synthesis. This compound serves as a crucial high-purity building block for the development of complex, biologically active molecules, offering precise stereochemical control. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Peptidomimetic Chemistry: Used to introduce the (2R)-2-hydroxypentyl moiety into peptide backbones to modulate stability, bioavailability, and receptor binding.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in enantioselective catalysis.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides a base-labile protecting group for amines in multi-step synthetic sequences.
• Agrochemical Research: Employed in the discovery and development of novel, stereospecific herbicides and fungicides.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	Carbamic Acid, [(2R)-2-Hydroxypentyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	214679-14-8
Molecular Formula	C10H21NO3
Molecular Weight	203.28 g/mol
Synonyms	(R)-N-Boc-2-Hydroxypentylamine; (2R)-2-Hydroxy-N-[(2-methylpropan-2-yl)oxycarbonyl]pentan-1-amine; tert-Butyl ((2R)-2-hydroxypentyl)carbamate; N-Boc-(R)-2-Aminopentan-1-ol; Boc-D-Homoserinol; (R)-N-(tert-Butoxycarbonyl)-2-aminopentanol; (R)-2-((tert-Butoxycarbonyl)amino)pentan-1-ol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(2R)-2-Hydroxypentyl]-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.