Description

4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Fluorobenzene is a high-purity, synthetically valuable boronic ester derivative, widely recognized as a key building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aryl groups.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the fluorophenylboronate moiety into target molecules.
• Material Science: Serves as a monomer or functionalization agent in the production of organic electronic materials, such as OLEDs and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic chemistry.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Fluorine Chemistry: Specifically valuable for incorporating fluorine atoms into complex organic molecules to modulate their physicochemical properties.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Fluorobenzene
CAS No.	214360-58-4
Molecular Formula	C12H16BFO2
Molecular Weight	222.07 g/mol
Synonyms	4-Fluorophenylboronic acid pinacol ester; 1-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; p-Fluorophenylboronic acid pinacol ester; 4-Fluorobenzene-1-boronic acid pinacol ester; (4-Fluorophenyl)boronic acid pinacol ester; 4-FBPin; 4-FluorophenylBPin; CAS 214360-58-4
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Fluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and GC analysis, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the primary container to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.