Description

n-[(1R,2R)-2-Hydroxycyclohexyl]- Acetamide is a high-purity, stereochemically defined chiral acetamide derivative. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile chiral building block for complex organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for creating novel, enantiomerically pure pesticides and herbicides with enhanced efficacy and environmental profiles.
• Fine Chemical Production: Serves as a precursor in the synthesis of specialty chemicals, ligands, and catalysts requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent for methodological studies in asymmetric synthesis and medicinal chemistry research programs.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of chiral molecules.

Basic Information

Product Name	n-[(1R,2R)-2-Hydroxycyclohexyl]- Acetamide
CAS No.	214348-95-5
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1R,2R)-2-Acetamidocyclohexanol; N-[(1R,2R)-2-Hydroxycyclohexyl]acetamide; (1R,2R)-N-(2-Hydroxycyclohexyl)acetamide; trans-2-Acetamidocyclohexanol; Acetamide, N-[(1R,2R)-2-hydroxycyclohexyl]-; Chiral Cyclohexyl Acetamide Derivative; (1R,2R)-2-Hydroxy-N-acetylcyclohexylamine
EINECS	Contact for details

Quality Control

Our n-[(1R,2R)-2-Hydroxycyclohexyl]- Acetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, impurity profile, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.