Description

4-Bromo-N-(2,2,2-trifluoroethyl)benzamide is a high-purity, fluorinated benzamide derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable pharmaceutical intermediate and building block for the development of novel active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the trifluoroethyl group for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal chemistry.
• Material Science Precursor: Potential use in the synthesis of monomers for specialty polymers with unique thermal and chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-Bromo-N-(2,2,2-trifluoroethyl)benzamide
CAS No.	214261-65-1
Molecular Formula	C9H7BrF3NO
Molecular Weight	282.06 g/mol
Synonyms	4-Bromo-N-(2,2,2-trifluoroethyl)benzamide; Benzamide, 4-bromo-N-(2,2,2-trifluoroethyl)-; N-(2,2,2-Trifluoroethyl)-4-bromobenzamide; p-Bromo-N-(2,2,2-trifluoroethyl)benzamide; 4-Bromo-2,2,2-trifluoroethylbenzamide; 214261-65-1; 4-Bromo-alpha,alpha,α-trifluoro-N-ethylbenzamide
EINECS	Contact for details

Quality Control

Our 4-Bromo-N-(2,2,2-trifluoroethyl)benzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.